Spectroscopic Characterization of Intermolecular Interaction of AmyloidβPromoted on GM1 Micelles
نویسندگان
چکیده
منابع مشابه
Spectroscopic Characterization of Intermolecular Interaction of Amyloid β Promoted on GM1 Micelles
Clusters of GM1 gangliosides act as platforms for conformational transition of monomeric, unstructured amyloid β (Aβ) to its toxic β-structured aggregates. We have previously shown that Aβ(1-40) accommodated on the hydrophobic/hydrophilic interface of lyso-GM1 or GM1 micelles assumes α-helical structures under ganglioside-excess conditions. For better understanding of the mechanisms underlying ...
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ژورنال
عنوان ژورنال: International Journal of Alzheimer's Disease
سال: 2011
ISSN: 2090-0252
DOI: 10.4061/2011/925073